DAY 1 - 30th March 2023
8:30 – 8:45 8.30 – 9:00 | Registration CME Welcome |
9:00 – 9:20 | Overview on genetic in axSpA | Matthew Brown |
9:20 – 9:40 | Polygenic risk score in biomedical research | Richard Oram |
9:40 – 10:00 | Polygenic risk scores in axSpA | Huji Xu |
10:00 – 10:20 | Functional evaluation of ERAP1 in axSpA | Tony Kenna |
10:20 – 10:40 | Questions and Discussion (Regarding the subject included in the session) | interactive |
from 10:40 to 11:00
11:00 – 11:20 | Exploring rare variants in multicase Families | Felicie Costantino |
11:20 – 11:40 | News from B27 transgenic drosophila | Vincent Rincheval |
11:40 – 12:00 | Functional genomics in axSpA | Matteo Vecellio |
12:00 – 12:15 | Questions and Discussion (Regarding the subject included in the session) | Interactive |
12:15 – 12:25 | Validating the arthritogenic hypothesis: connections between gut and entheseal immunity | Jose Garrido Mesa |
12:25 – 12:35 | Identifying causal relationships between gut microbiome and axSpA through mendelian randomization | Nicholas Harvey |
12:35 – 12:45 | Exploring TLR signaling in DC from HLA-B27 transgenic rat | Ait Ali Said Amel |
12:45 – 1:00 | Discussion (Regarding the subject included in the session) |
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from 1:00 PM to 2:00 PM
2.00 – 2:20 | Microbiome and axSpA pathogenesis | Maxime Breban |
2:20 – 2:40 | The role of gut bacteria in the development of Spondyloarthritis | Anne Sophie Bergot |
2:40 – 3:00 | Fecal microbial transplantation in axSpA | Maja Kragsnæs |
3:00 – 3:20 | Questions and Discussion (Regarding the subject included in the session) | Interactive |
From 3:20 PM to 3:40 PM
3:40 – 4:00 | Gut and axSpA: evidence and controversies | Francesco Ciccia |
4.00 – 4:20 | News from the gut in axSpA | Thomas Bazin |
4:20 – 4:40 | Modulation of epithelial intestinal barrier in the pathogenesis of inflammatory arthritis | Aline Bozec |
4:40 -5:00 | New mucosal player in axSpA pathogenesis | Daniele Mauro |
5:00 – 5:20 | Questions and Discussion (Regarding the subject included in the session)
| Interactive |
DAY 2 - 31st March 2023
8.50 – 09:10 | Co-receptors in helper and cytotoxic T cells function | Ondrej Stepanek |
09:10 – 09:30 | DCs and Th17 interaction in B27 transgenic rat | Simon Glatigny |
09:30 – 09:50 | Single cell insights into the immunology of axSpA | Davide Simone |
09:50 – 10:10 | Autoimmunity-associated T cell receptors recognize HLA-B*27-bound peptides | Paul Bowness |
10:10 – 10:30 | Questions and Discussion (Regarding the subject included in the session) | interactive |
From 10:30 AM to 10:50 AM
| 10:50 – 11:10 | TCR immunology | Jia Jia Lim |
| 11:10 – 11:30 | Interleukin 17 inhibitors and the effect on enthesitis and pain in Spondyloarthritis | Marije Koenders |
| 11.30 – 11.50 | Immunopathogenesis of enthesistis in axSpA | Dennis Mc Gonagle |
| 11.50 – 12.10 | Questions and Discussion (Regarding the subject included in the session) |
from 12:10 PM to 1:30 PM
1:30 – 1:50 | MIF: a potential therapeutic target in axSpA | Nigil Haroon |
1:50 – 2:10 | Dysregulated CTL Exhaustion in axSpA | Michael Tang |
2:10 – 2:30 | ZRANB1 in AS pathogenesis | Archita Shrinath |
2:30 – 3:00 | Questions and Discussion (Regarding the subject included in the session) | Interactive |
From 3:00 PM to 3:20 PM
| 3:20 – 3:40 | Immune tolerance and resolution of inflammation in inflammatory arthritis | Stefano Alivernini |
| 3:40 – 4:00 | Metabolic control of Innate lymphoid cells | Chen Dong |
| 4:00 – 4:20 | Questions and Discussion (Regarding the subject included in the session) | Interactive |
4:20 – 4:30 | Profiling T cell receptor polymorphisms in axSpA | Zoya Qaiyum |
4:30 – 4:40 | Leaky gut in SpA: focus on ZEB proteins | Chiara Rizzo |
4:40 – 4:50 | How does TGFb affect CD4+ T cell response in axSpA? | Marc Lauraine |
4:50 – 5:05 | Discussion (Regarding the subject included in the session) |
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5:05 – 5:25 | The lecture has not been included in the educational program CME From patient side: the role of Ixekizumab in patient reported outcomes | Ennio Favalli |
5:25 – 5:45 | The lecture has not been included in the educational program CME The recognition and management of early PsA: which role for the IL23 inhibitor GuselKumab?
| Ilenia Pantano |
DAY 3 - 1st April 2023
| 8:30 – 8:50 | Immune-stromal interaction in bone formation | Nicole Horwood |
| 8:50 – 9:10 | Mechano-inflammation in axSpA | Dirk Elewaut |
| 9:10 – 9:30 | Fibroblast Activation Protein (FAP) PET-CT for depicting osteoproliferation in axSpA patient | Andreas Ramming |
| 9:30 – 9:50 | Questions and Discussion (Regarding the subject included in the session) | interactive |
| 9:50 – 10:10 | Sex-specific differences in axSpA: myth or truth? | Irene Van der Host-Bruinsma |
| 10:10 – 10:30 | Sex differences in treatment efficacy of interleukin 17 inhibitors in Spondyloarthritis | Emmerik Leijten |
| 10:30 – 10:50 | Insight in PsA by imaging | AGeorg Schett |
| 10:50 – 11:00 | Questions and Discussion (Regarding the subject included in the session) | interactive |
11:10 – 11:30 | Biomarkers predictive of clinical response in AxSpA | John Reveille |
11:30 – 11:50 | ASAS-Eular recommendations for the management of AxSpA | Lianne Gensler |
11.50 – 1 2.10 | The added value of sonography in SpA diagnosis and monitoring | Maria Antonietta D’Agostino |
12:10 – 12.30 | Questions and Discussion (Regarding the subject included in the session) | Interactive |
| 12:30 – 12:40 | Comorbidities and metabolic burdern in early PSA: data from prospective metapsa cohort | Alla Ishchenko |
| 12:40 – 12:50 | Cytof profiling of blood populations in axSpA” | Claudia Worth |
| 12:50 – 1:00 | IL-24 as biomarkers in axSpA | Giulio Forte |
| 1:00 – 1:15 | Discussion (Regarding the subject included in the session) |
1:15- 1:25 | “Mark Asquith” award for best young presentation |
From 1:25 PM to 2:25 PM
From 2:25 PM to 3:00 PM
SCIENTIFIC INFORMATION
SPEECHES IN THE AUDITORIUM
Time of presentation is 20 minutes for the speech.
Speakers must present scientific material only in power point format (16:9).
Lap top computers are not allowed.
Only one system will automatically provide to forward into the Auditorium the entire projection.
CERTIFICATE OF ATTENDANCE
Certificates of Attendance will be available on request starting from Saturday, April 1st at the Registration Desk.
SLIDE CENTER
The Slide Center is available in the room A Speakers are requested to load their slides in the Slide Center at least 2 hours before presentation..
The opening hours of the slide center are:
Thursday, March 30th, from 07:30 to 18:30
Friday, March 31st, from 07.30 to 18:30
Saturday, April 1st, from 07:30 to 18.00
CME
The provider Associazione Sinapsy Soluzioni e Servizi Integrati according to the present Ministerial set of rules has assigned 17 CME points to Conference ”International Genetics of Ankylosing Spondylitis Consortium” IGAS.
Discipilines: Rheumatology, Internal Medicine, Allergology and Clinical Immunology.